Research Areas

RESEARCH PROJECTS CURRENTLY BEING CONDUCTED

                  NAME                                  

                    SUBJECT OF RESEARCH

Prof. Nadira Karunaweera

  • Multicentre study of immune gene polymorphisms that determine antibody production to malaria antigen in collaboration with the Wellcome Trust Centre for Human Genetics, Oxford, UK.
  • Studies on genetic diversity of malaria parasites in collaboration with the Harvard School of Public Health, USA.
  • An epidemiological study on disease prevalence and risk factors of leishmaniasis in Southern Sri Lanka in Sri Lanka.
  • Establishment of a novel serological assay for the diagnosis of leishmaniasis in Sri Lanka.
  • Species characterization and clinical profile determination for L.donovani  infections in Sri Lanka.
  • Screening for Glucose-6-Phosphate Dehydrogenase (G6PD) enzyme deficiency among a selected population within the districts of Kurunegala and Anuradhapura.
  • Determination of genetic variants associated with G6PD enzyme deficiency in selected Sri Lankan populations.
  • Defining host responses and parasite genetics in the context of malaria elimination in Sri Lanka.

Prof. Deepika Fernando

  • Malaria surveillance and therapeutic response to anti malaria drugs.
  • Multicentre study of immune gene polymorphisms that determine antibody production to malaria antigen” in collaboration with the Wellcome Trust Centre for Human Genetics, Oxford, UK.
  • Host genetic susceptibility in patients with cutaneous leishmaniasis.
  • A sero-epidemiology study of leptospirosis in the Colombo district.
  • Antibody testing of clinically diagnosed malaria patients in the Eastern Province.

Dr. Sharmini Gunawardena

  • Studies on genetic diversity of malaria parasites in collaboration with the Harvard School of Public Health, USA.
  • Screening for Glucose-6-Phosphate Dehydrogenase (G6PD) enzyme deficiency among a selected population within the districts of Kurunegala and Anuradhapura.
  • Determination of genetic variants associated with G6PD enzyme deficiency in selected Sri Lankan populations.
  • Defining host responses and parasite genetics in the context of malaria elimination in Sri Lanka.

Dr. Yamuna Siriwardena

  • An epidemiological study on disease prevalence and risk factors of leishmaniasis in Southern Sri Lanka in Sri Lanka.
  • Establishment of a novel serological assay for the diagnosis of leishmaniasis in Sri Lanka.
  • Species characterization and clinical profile determination for L.donovani  infections in Sri Lanka.

Dr Sanath Senanayake

  • Role of salivary secretions of Phlebotomus argentipes(var  glaucus) in pathogenicity of Leismania donovani induced Leishmania infections.

Dr. Nilakshi Samaranayake

  • Host genetic susceptibility in patients with cutaneous leishmaniasis HLA diversity in patients with cutaneous leishmaniasis.
  • Defining the role of the innate cellular immune response in determining outcome in infection due to L. donovani.

Dr. Hermali Silva

  • Study on treatment of leishmaniasis.

Dr. Sisira Pathirana

  • Studies on identification of genes coding strain-specific protective immunity to Plasmodium infection
  • Evaluation of maternal antibody levels against measles, mumps and rubella in Sri Lankan infants.
  • Association between human socioeconomic development and malaria infection.