Human Genetics Unit – Research

Sri Lankan Personal Genom

Launch of the Sri Lankan Personal Genome on 10 December 2010 at the Annual Scientific Sessions of the Sri Lanka Association for the Advancement of Science in Colombo, Sri Lanka. The hard disk containing the Sri Lankan Personal Genome is being handed over to the Senior Minister for Scientific Affairs Hon. Prof. Tissa Vitharana by Prof. Vajira H. W. Dissanayake, Chairperson, Specialty Board in Biomedical Informatics and Dr. Rajesh Gokhale, Director Institute of Genomics and Integrative Biology, India.

Sri Lankan Genetic variation Database

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The list of research grants received by the Unit and its collaborative partners from the year 2002 onwards is given below.

  1. 2013, University Grants Commission, Sri Lanka– Innovative Research Grants – Rs. 32,000,000/-  Funding for Stem Cell Research and Development.
  2. 2012, University of Colombo – AP/3/2012/PG/03: Rs. 1,500,000/- , As partial funding for the research project “Associations between lumbar intervertebral disc severity of mechanical low back pain (LBP), associated factors, severity of disability and treatment outcomes among a cohort of patients in degeneration (LIDD) and Anatomy, Faculty of Medicine, University of Kelaniya.
  3. 2012, University of Colombo – AP/3/2011/PG/14: Rs. 1,500,000/-, As partial funding for the research project “A molecular genetic study of bladder cancer in the Sri Lankan Sinhalese population” of Dr. Ajith Malalaseskara, PhD student.
  4. 2011, University Grants Commission – Grant No. UGC/ICD/GR2011/02/07: Rs. 1,000,000/-,  As partial funding for the research project “A molecular genetic study of bladder cancer in the Sri Lankan Sinhalese population” of Dr. Ajith Malalaseskara, PhD student.
  5. 2011, European Social Research Council, Research Grant: £ 21,316,  For the international collaborative study on “Biomedical and Health Experimentation in South Asia: Critical Perspectives on collaboration, governance and competition” involving University of Durham, UK; Centre for Social and Ethical Research, Mumbai, India, Social Science Baha, Nepal and University of Colombo, Sri Lanka.
  6. 2009, Norwegian Centre for International Cooperation in Higher Education. Norad’s Programme for Master Studies (NOMA) – NOK 2,525,000 (approx: Rs. 50,500,000),  To conduct an MSc Course and Research in Medical and Bioinformatics for an additional two years.
  7. 2009, Norwegian Centre for International Cooperation in Higher Education. Norad’s Programme for Master Studies (NOMA) – NOK 5,994,000 (approx: Rs. 119,880,000)  To conduct an MSc Course and Research in Clinical Genetics and Genetic Diagnostics.
  8. 2009, Norwegian Centre for International Cooperation in Higher Education. Norad’s Programme for Master Studies (NOMA) – NOK 200,000 (approx: Rs. 4,000,000)  This is a start up grant to establish collaboration with the Department of Medical Genetics of the University of Oslo to develop and conduct MSc Courses and Research in Genetics.
  9. 2008, National Institute of Health, Maryland, USA Research Grant: US$ 16,630   For a study of Values at the Bedside: A Survey of Sri Lankan Physicians Regarding   Ethical Dilemmas in Clinical Practice.Role – Co-Investigator (Principal Investigator – Dr. Marion Dannis, NIH, USA).
  10. 2008, Information Communication Technology Agency – Partnership Assistant Project Grant No: ICTA/CON/74/20 – Rs. 5,000,000  To develop a health education website in Sinhala and Tamil for the general public. The website is now online at http://www.wedananasala.org
  11. 2007, National Institute of Health, Maryland, USA Research Grant: US$ 1150   For the Sri Lanka component of an International Survey of Scientists and Policy Makers’ Attitudes Toward Research on Stored Human Biological Materials.
  12. 2007, The Norwegian Centre for International cooperation in Higher Education. Norad’s Programme for Master Studies (NOMA) – NOK 6,000,000 (approximately Rs. 120,000,000)  To develop and conduct an MSc Course and Research in Medical and Bioinformatics.
  13. 2007, Information Communication Technology Agency – Community Assistance Project Grant No: ICTA/CON/73/C034 – Rs. 612,000  To provide distance genetic consultation services using the Internet to rural communities – the tele-genetics project.
  14. 2006, IRQUE Project Research Grants for Staff Student Collaborative Research 2006: Grant No – 2006-4: Rs. 150,000/-  A study of genetic factors at the maternal-fetal interface that predispose to adult onset cardiovascular disease, hypertension, and diabetes.
  15. 2006, IRQUE Project Research Grants for Staff Student Collaborative Research 2006: Rs. 150,000/-  For a study of genetic variants in the CYP2D6 gene in the Sri Lankan population.
  16. 2005, IRQUE Project Research Grants for Staff Student Collaborative Research 2005: Rs. 150,000/-  For the study of prevalence of the Factor V 4070A>G polymorphism in the Sri Lankan population.
  17. 2005, IRQUE Project Research Grants for Staff Student Collaborative Research 2005: Rs. 150,000/-   For the candidate gene association study of genetic susceptibility to cutaneous leishmaniasis.
  18. 2005, National Research Council Research Grants 2005 – Grant No 05-15: Rs. 3,799,980/-  For the study of Inherited factors in pre-eclampsia and weight of babies at birth: Investigations on the role of the epidermal growth factor (EFG) gene.
  19. 2005, University Grants Commission – Grant No. RPC/2005/2i/CMB: Rs. 300,000/-  For the candidate gene association study of genetic susceptibility to cutaneous leishmaniasis.
  20. 2005, National Science Foundation – Grant No SIDA/2005/BT/04: Rs. 945,220/-  For the study of the association of genetic thrombophilic polymorphisms with recurrent pregnancy loss.
  21. 2005, National Science Foundation – Grant No RG/2005/EQ/02: Rs. 998,960/-  This is an equipment grant to buy a -80oC Freezer for bio banking.
  22. 2004, National Science Foundation – Grant No SIDA/2004/BT/01: Rs. 2,238,000/- , For the study of the frequency of genetic thrombophilic polymorphisms in the Sri Lankan population and the association of these polymorphisms with pre-eclampsia.
  23. 2004, University of Colombo Development Fund – Rs. 4,800,000/- , To automate the cytogenetic diagnostic service.
  24. 2004, Faculty of Medicine Development Fund – Rs. 1,500,000/-  To set up a molecular genetic diagnostic laboratory.
  25. 2002, Sri Lanka Medical Association – Glaxo Welcome Research Award 2002: Rs. 50,000/-  For the project proposal titled “Does urinalysis by the heat coagulation method performed by midwives in the ward reliably predict significant proteinuria?”