Leishmaniasis Research (TMRC/ NIH Project)

Welcome to the official website of TMRC Project – Sri Lanka.

We are a research center funded through a grant facilitated by National Institute of Health, USA, incorporated with the Faculty of Medicine, University of Colombo, Sri Lanka. The collaborations built through the TMRC award are designed to facilitate research on the cause, diagnosis, disease pathology, pathogenesis, effective disease management, prevention, control and to create and sustain in-country research capacity with strengthened international collaborations on Leishmaniasis disease. The ongoing studies continue to provide critical information in a systematic manner, on many aspects of leishmaniasis with a special focus on diagnosis, patient management, epidemiology, vector ecology and transmission, which are desperately needed for national-level planning of leishmaniasis control and subsequent elimination both in Sri Lanka and Bhutan. The project is supervised and guided by Senior Professor Nadira Karunaweera and Senior Professor and Chair of Parasitology in collaboration with the University of California, Irvine, USA and the Khesar-Gyalpo University of Medical Sciences of Bhutan.

We are one of the seven TMRC research centers located throughout world, funded by the National Institute of Allergy and Infectious Diseases (NIAID) , National Institute of Health (NIH),USA through a highly competitive and respected TMRC grant awarded once in every five years. After the award was granted in the year of 2017, the research project was initiated by a team at the Parasitic Disease Research Unit (PDRU), Faculty of Medicine, University of Colombo. This funding support from the NIH, USA to the University of Colombo in 2017, was a continuation of financial support that started in 2012 through an R01 Award (NIH AI099602) that sponsored the pioneering research program on Leishmaniasis that Sr.Prof. Karunaweera and her team continues since the year 2001 (with the initial funding support coming from the National Science Foundation, Sri Lanka and the University of Colombo).

The concentration of the study is mainly divided into three parts.

  • Understanding the occurrence, the disease process in humans, it’s management and the spread of leishmaniasis in Sri Lanka and Bhutan using biological, epidemiological and molecular tools.
  • Dissecting the role and properties of the vector and its environment to enable infection control in Sri Lanka and Bhutan.
  • Investigating genetic factors in Phlebotomus argentipes associated with transmission efficiency and dynamics in Sri Lanka.

 

One of the main responsibilities of TMRC is to communicate the new science it discovers to a range of audiences, such as the general public, scientific community, university students, and school children. It carries out various programs throughout the year to fulfill this responsibility using many channels especially social media platforms.

Announcements

Dr. Leonard’s visit to PDRU

Dr. Leonard Munstermann, Senior Research Scientist in Epidemiology from Yale Institute for Global Health, visited the PDRU laboratory, from 25th May to 7th June 2019. He conducted field experiments with the Entomological team of the TMRC team. Dr. Munstermann works as the head curator of Entomology in Yale Peabody Museum of Natural History, USA.

Training for Technical Officers from Bhutan at the PDRU laboratory on molecular identification of leishmaniasis

Two Bhutanese trainees Mr Dorji Tshering and Mr Rinchen Dorji from the Royal Centre for Disease Control (RCDC), Ministry of Health, Thimphu, Bhutan completed a training session on PCR and ELISA for detection of leishmaniasis at the Parasitic Diseases Research Unit (PDRU) laboratory, Department of Parasitology, Faculty of Medicine, University of Colombo during 23rd-29th of October 2022. The second phase of this…

Donation of ‘Radio-Frequency Heat Therapy (RFHT) machines

The handing over ceremony of 2 Radio-Frequency Heat Therapy (RFHT) machines, each costing over 1.5 million LKR, was made by the Head of Leishmaniasis Program at the Drugs for Neglected Diseases Initiative (DNDi) in Geneva, Switzerland, Dr. Byron Arana was held on Friday, 28th July 2023 at the Dean’s Office, Faculty of Medicine, Colombo. These…
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