Centre For Training Research & Diagnosis Of Leishmaniasis – Publications

Publications by author

Publications by subject

Clinical epidemiology

Siriwardana HVYD, Deepachandi B, Weliange S de S, Udagedara C, Wickremarathne C, Warnasuriya W, Ranawaka RR., Kahawita I, Chandrawansa PH, Karunaweera ND. First evidence for two independent and different leishmaniasis transmission foci in Sri Lanka. Recent introduction or long term existence? Journal of Tropical Medicine. vol. 2019, Article ID 6475939, 11 pages, 2019. read more
Siriwardana HVYD, Deepachandi B, Gunasekara C, Warnasooriya W, Karunaweera ND. Leishmania donovani induced cutaneous leishmaniasis: an insight into atypical clinical variants in Sri Lanka. J Trop Med. 2019 May 27;2019:4538597. doi: 10.1155/2019/4538597. read more
Siriwardana HVYD, Zhou G, Deepachandi B, Akarawita J, Wickremarathne C, Warnasuriya W, Udagedara C, Ranawaka RR, Kahawita I, Ariyawansa D, Sirimanna G, Chandrawansa PH, Karunaweera ND. Trends in recently emerged Leishmania donovani induced cutaneous leishmaniasis, Sri Lanka, for the first 13 years. Biomed Res Int. 2019 Apr 14;2019:4093603. doi: 10.1155/2019/4093603. read more
Kariyawasam KKGDUL, Selvapandiyan A, Siriwardana HVYD, Dube A, Karunanayake P, Senanayake SASC, Dey R, Gannavaram S, Nakhasi HL, Karunaweera ND. Dermotropic Leishmania donovani in Sri Lanka: visceralizing potential in clinical and preclinical studies. Parasitology. 2018 Apr;145(4):443-452. doi: 10.1017/S003118201700169X. read more
Siriwardana HVYD, Karunanayake P, Goonerathne L, Karunaweera ND. Emergence of visceral leishmaniasis in Sri Lanka: a newly established health threat. Pathog Glob Health. 2017 Sep;111(6):317-326. doi: 10.1080/20477724.2017.1361564. read more
Kariyawasam KK, Edirisuriya CS, Senerath U, Hensmen D, Siriwardana HVYD, Karunaweera ND. Characterisation of cutaneous leishmaniasis in Matara district, southern Sri Lanka: evidence for case clustering. Pathog Glob Health. 2015;109(7):336-43. doi: 10.1179/2047773215Y.0000000032. read more
Rathnayake D, Ranawake RR, Sirimanna G, Siriwardhane HVYD, Karunaweera N, De Silva R. Co-infection of mucosal leishmaniasis and extra pulmonary tuberculosis in a patient with inherent immune deficiency. Int J Dermatol. 2010 May;49(5):549-51. doi: 10.1111/j.1365-4632.2010.04376.x. read more
Siriwardana HVYD, Thalagala N, Karunaweera ND. Clinical and epidemiological studies on the cutaneous leishmaniasis caused by Leishmania (Leishmania) donovani in Sri Lanka. Ann Trop Med Parasitol. 2010 Apr;104(3):213-23. doi: 10.1179/136485910X12647085215615. read more
Rajapaksa US, Ihalamulla RL, Karunaweera ND. First report of mucosal tissue localization of leishmaniasis in Sri Lanka. Ceylon Med J. 2005 Jun;50(2):90-1. read more
Siriwardana HVYD, Udagedara CU, Karunaweera ND. Clinical features, risk factors and efficacy of cryotherapy in cutaneous leishmaniasis in Sri Lanka. Ceylon Med J. 2003 Mar;48(1):10-2. read more

Sandfly vectors

Senanayake SA, Abeyewicreme W, Dotson EM, N D Karunaweera. Characterization of Phlebotomine sandflies in selected areas in Sri Lanka. Southeast Asian J Trop Med Public Health. 2015 Nov;46(6):994-1004. read more

Parasite species/ strain variation

Samarasinghe SR, Samaranayake N, Kariyawasam UL, Siriwardana HVYD, Imamura H, KarunaweeraND. Genomic insights into virulence mechanisms of Leishmania donovani: evidence from an atypical strain. BMC Genomics. 2018 Nov 28;19(1):843. doi: 10.1186/s12864-018-5271-z. read more
Kariyawasam UL, Selvapandiyan A, Rai K, Wani TH, Ahuja K, Beg MA, Premathilake HU, Bhattarai NR, Siriwardana HVYD, Zhong D, Zhou G, Rijal S, Nakhasi H, Karunaweera ND. Genetic diversity of Leishmania donovani that causes cutaneous leishmaniasis in Sri Lanka: a cross sectional study with regional comparisons. BMC Infect Dis. 2017 Dec 22;17(1):791. doi: 10.1186/s12879-017-2883-x. read more
Siriwardana HVYD, Noyes HA, Beeching NJ, Chance ML, Karunaweera ND, Bates PA. Leishmania donovani and cutaneous leishmaniasis, Sri Lanka. Emerg Infect Dis. 2007 Mar;13(3):476-8. read more
Karunaweera ND, Pratlong F, Siriwardane HVYD, Ihalamulla RL, Dedet JP. Sri Lankan cutaneous leishmaniasis is caused by Leishmania donovani zymodeme MON-37. Trans R Soc Trop Med Hyg. 2003 Jul-Aug;97(4):380-1. read more

Patient diagnosis, serology and other investigations

Deepachandi B, Weerasinghe S, Soysa P, Karunaweera N, Siriwardana HVYD. A highly sensitive modified nested PCR to enhance case detection in leishmaniasis. BMC Infect Dis. 2019 Jul 15;19(1):623. doi: 10.1186/s12879-019-4180-3. read more
Ejazi SA, Ghosh S, Saha S, Choudhury ST, Bhattacharyya A, Chatterjee M, Pandey K, Das VNR, Das P, Rahaman M, Goswami RP, Rai K, Khanal B, Bhattarai NR, Deepachandi B, Siriwardana HVYD, Karunaweera ND, deBrito MEF, Gomes YM, Nakazawa M, Costa CHN, Adem E, Yeshanew A, Melkamu R, Fikre H, Hurissa Z, Diro E, Carrillo E, Moreno J, Ali N. A multicentric evaluation of dipstick test for serodiagnosis of visceral leishmaniasis in India, Nepal, Sri Lanka, Brazil, Ethiopia and Spain. Sci Rep. 2019 Jul 9;9(1):9932. doi: 10.1038/s41598-019-46283-9. read more
Siriwardana HVYD, Deepachandi B, Ranasinghe S, Soysa P, Karunaweera N. Evidence for sero-prevalence in human localized cutaneous leishmaniasis caused by Leishmania donovani in Sri Lanka. Biomed Res Int. 2018 Jan 17;2018:9320367. doi: 10.1155/2018/9320367. read more
Manamperi NH, Chandu de Silva MV, Pathirana N, Abeyewickreme W, Karunaweera ND. Tissue impression smears as a supplementary diagnostic method for histopathology in cutaneous leishmaniasis in Sri Lanka. Am J Trop Med Hyg. 2018 Mar;98(3):759-762. doi: 10.4269/ajtmh.17-0748. read more
Manamperi NH, Oghumu S, Pathirana N, de Silva MV, Abeyewickreme W, Satoskar AR, Karunaweera ND. In situ immunopathological changes in cutaneous leishmaniasis due to Leishmania donovani. Parasite Immunol. 2017 Mar;39(3). doi: 10.1111/pim.12413. read more
Kothalawala HS, Karunaweera ND. Loop-mediated isothermal amplification assay as a sensitive diagnostic tool for Leishmania donovani infections in Sri Lanka. Ceylon Med J. 2016 Jun;61(2):68-70. doi: 10.4038/cmj.v61i2.8286. read more
Siriwardana HVYD, Senarath U, Chandrawansa PH, Karunaweera ND. Use of a clinical tool for screening and diagnosis of cutaneous leishmaniasis in Sri Lanka. Pathog Glob Health. 2015 Jun;109(4):174-83. doi: 10.1179/2047773215Y.0000000024. read more
Ihalamulla RL, Rajapaksa US, Siriwardena HVYD, Chance M, Karunaweera ND. A simple, cost effective method for isolation and transportation of Leishmania parasites. Ceylon Med J. 2009 Jun;54(2):46-7. Doi: 10.4038/cmj.v54i2.864
Ihalamulla RL, Siriwardana HVYD, Karunaweera ND. Efficacy of RPMI 1640 and M 199 media in the isolation of Leishmania from cutaneous lesions. Ann Trop Med Parasitol. 2008 Mar;102(2):173-5. doi: 10.1179/136485908X252331. read more
Ihalamulla RL, Rajapaksa US, Karunaweera ND. Microculture for the isolation of Leishmania parasites from cutaneous lesions – Sri Lankan experience. Ann Trop Med Parasitol. 2005 Sep;99(6):571-5. read more
Ihalamulla RL, Liyanage CP, Karunaweera ND. A simple device to maintain in vitro cultures of Leishmania in tropical countries. Trans R Soc Trop Med Hyg. 2004 May;98(5):315-7. read more
Ihalamulla RL, Siriwardana HVYD, Gamage S, Perera AJ, Karunaweera ND. First successful in vitro culture of autochthonous Leishmania sp. in Sri Lanka. Ceylon Med J. 2002 Jun;47(2):58. read more

Human genetics

Samaranayake N, Fernando SD, Neththikumara NF, Rodrigo C, Karunaweera ND, Dissanayake VH. Association of HLA class I and II genes with cutaneous leishmaniasis: a case control study from Sri Lanka and a systematic review. BMC Infect Dis. 2016 Jun 14;16:292. doi: 10.1186/s12879-016-1626-8. read more
Samaranayake TN, Fernando SD, Dissanayake VH. Candidate gene study of susceptibility to cutaneous leishmaniasis in Sri Lanka. Trop Med Int Health. 2010 May;15(5):632-8. doi: 10.1111/j.1365-3156.2010.02491.x. read more
T.N.Samaranayake, V.H. Dissanayake, S.D. Fernando (2008). Clinical manifestations of cutaneous leishmaniasis in Sri Lanka- possible evidence for genetic susceptibility among the Sinhalese. Annals of Tropical Medicine and Parasitology, 102 (5): 383-390. read more

Treatment aspects

Refai WF, Madarasingha NP, Sumanasena B, Weerasingha S, Fernandopulle R, Karunaweera ND. Cutaneous leishmaniasis in Sri Lanka: effect on quality of life. Int J Dermatol. 2018 Dec;57(12):1442-1446. doi: 10.1111/ijd.14240.
Refai WF, Madarasingha NP, Sumanasena B, Weerasingha S, De Silva A, Fernandopulle R, Satoskar AR, Karunaweera ND. Efficacy, safety and cost-effectiveness of thermotherapy in the Treatment of Leishmania donovani-induced cutaneous leishmaniasis: a randomized controlled clinical trial. Am J Trop Med Hyg. 2017 Oct;97(4):1120-1126. doi: 10.4269/ajtmh.16-0879. read more
Refai FW, Madarasingha NP, Fernandopulle R, Karunaweera N. Non-responsiveness to standard treatment in cutaneous leishmaniasis: a case series from Sri Lanka. Trop Parasitol. 2016 Jul-Dec;6(2):155-158. read more

Research reviews

Karunaweera ND. Leishmaniasis: Path toward elimination from the Indian subcontinent. Trop Parasitol. 2016 Jan-Jun;6(1):2-4. https://doi: 10.4103/2229-5070.175023 read more
Siriwardana HVYD, Sirimanna G, Chandrawansa PH, Karunaweera ND. Leishmaniasis in Sri Lanka: a decade old story. Sri Lanka Journal of Infectious Diseases, 2012:2 (2);2-12. read more
Siriwardana HVYD, Karunaweera ND. Leishmaniasis in Sri Lanka: atypical cutaneous disease by an unusual parasite species. Sri Lanka Journal of Dermatologists, 2011 ; 15: 10-13. read more
Karunaweera ND. Leishmania donovani causing cutaneous leishmaniasis in Sri Lanka: a wolf in sheep’s clothing? Trends Parasitol. 2009 Oct;25(10):458-63. doi: 10.1016/j.pt.2009.07.002. read more